Some Forms Of Birth Control Linked To Higher Risk Of Stroke & Heart Attack

Even if as a woman you are not yet at a point in life in which you are ready to have children, please be aware that if you choose pregnancy prevention by means of various birth control methods, there may significant health risks involved.

In a new study found in the New England Journal of Medicine, Danish researchers have found that some contraceptives carry a small risk of stroke and heart attack, depending on the method and type of hormone used.

So who is at risk based on these results?

The researchers’ findings suggest a higher risk of stroke in particular for women using vaginal rings, and possibly hormonal skin patches — though the second finding was based on a smaller group of women and could have been due to chance.

The researchers on the new study, led by Dr. Ojvind Lidegaard from Copenhagen University Hospital, crunched the records of 1.7 million Danish women — essentially the entire female population age 15 to 49 — to assess the potential dangers. The women, all without a history of heart disease or cancer, were followed from 1995 to 2010.

Each individual woman’s risk was small. One in every 4,700 women had a stroke each year and one in every 9,900 suffered a heart attack.

Women taking contraceptive pills with a combination of estrogen and progestin tended to have a higher risk of stroke and heart attack than those not using hormonal contraception.

For some hormone combinations that difference could have been due to chance. But women using estrogen with norethindrone or desogesterel at certain doses, for example, had double the risk of both complications compared to non-users.

Dr. James Simon, a women’s health researcher at George Washington University in Washington, D.C. told Reuters Health other factors — such as the belief that a patch or a ring might be safer for women thought to be at risk — may explain the higher rate of stroke in that group.

Simon, who wasn’t involved in the new research, said the findings probably shouldn’t change how doctors prescribe birth control. The risks seen in the study, he said, pale in comparison to the risks of stroke, heart attack or death faced by women who get pregnant.

“None of the hormonal contraceptives studied… were associated with an excess risk of stroke that was unacceptable, considering their contraceptive and noncontraceptive benefits,” Dr. Diana Petitti of Arizona State University in Tucson wrote in an editorial accompanying the study.

Still, Simon said the new research “shows very little difference between the different pills for the same dose of estrogen, which will make women’s choices larger.”

Lidegaard told Reuters Health many women have used patches and rings “believing that these non-oral products could confer less risk. But this is definitely not the case.”

He said age is a key factor when considering risks.

“If you are 20 years old and you double your risk of (stroke), then you still have a very low risk because the absolute risk is so low,” he said. “On the other hand, if you are in the other path of reproductive age, especially in the 40s, you should consider not increasing your risk… further because it’s already increased due to your age.”

Simon said women who think the findings mean they should stop taking contraceptives are getting the wrong message, because the risks associated with pregnancy are so much greater.

This is the largest study, to date, to examine the risks of hormone-based birth control. Previous attempts to assess the risk of stroke or heart attack due to hormonal contraceptives have produced conflicting results.



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